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Prednisolone syrup storage. Consumer medicine information
Prednisolone (Oral Route) Proper Use - Mayo Clinic.
If you are a consumer or patient please visit this version. Prednisolone Sodium Phosphate Oral Solution 15 mg Prednisolone per 5 mL contains the following inactive ingredients: anti-bitter mask, high fructose corn syrup, edetate disodium, glycerin, grape flavor, hydroxyethylcellulose, methylparaben, potassium phosphate dibasic, potassium phosphate monobasic, purified water, and sodium saccharin.
Prednisolone sodium phosphate occurs as white or slightly yellow, friable granules or powder. It is freely soluble in water; soluble in methanol; slightly soluble in alcohol and in chloroform; and very slightly soluble in acetone and in dioxane. Its chemical structure is:. Naturally occurring glucocorticoids hydrocortisone , which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states.
Their synthetic analogs are primarily used for their potent anti-inflammatory effects in disorders of many organ systems. Prednisolone is a synthetic adrenocortical steroid drug with predominantly glucocorticoid properties. Some of these properties reproduce the physiological actions of endogenous glucocorticosteroids, but others do not necessarily reflect any of the adrenal hormones' normal functions; they are seen only after administration of large therapeutic doses of the drug.
The pharmacological effects of prednisolone which are due to its glucocorticoid properties include: promotion of gluconeogenesis; increased deposition of glycogen in the liver; inhibition of the utilization of glucose; anti-insulin activity; increased catabolism of protein; increased lipolysis; stimulation of fat synthesis and storage; increased glomerular filtration rate and resulting increase in urinary excretion of urate creatinine excretion remains unchanged ; and increased calcium excretion.
Depressed production of eosinophils and lymphocytes occurs, but erythropoiesis and production of polymorphonuclear leukocytes are stimulated. Inflammatory processes edema, fibrin deposition, capillary dilatation, migration of leukocytes and phagocytosis and the later stages of wound healing capillary proliferation, deposition of collagen, cicatrization are inhibited.
Prednisolone can stimulate secretion of various components of gastric juice. Suppression of the production of corticotropin may lead to suppression of endogenous corticosteroids.
Prednisolone has slight mineralocorticoid activity, whereby entry of sodium into cells and loss of intracellular potassium is stimulated. This is particularly evident in the kidney, where rapid ion exchange leads to sodium retention and hypertension. Prednisolone is rapidly and well absorbed from the gastrointestinal tract following oral administration. It is metabolized mainly in the liver and excreted in the urine as sulfate and glucuronide conjugates. The systemic availability, metabolism and elimination of prednisolone after administration of single weight-based doses 0.
Results showed that the systemic availability of total and unbound prednisolone, as well as interconversion between prednisolone and prednisone were independent of age. The mean unbound fraction of prednisolone was higher, and the steady-state volume of distribution Vss of unbound prednisolone was reduced in elderly patients. Despite these findings of higher total and unbound prednisolone concentrations, elderly subjects had higher AUCs of cortisol, suggesting that the elderly population is less sensitive to suppression of endogenous cortisol or their capacity for hepatic inactivation of cortisol is diminished.
Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment in adult and pediatric populations with: seasonal or perennial allergic rhinitis; asthma; contact dermatitis; atopic dermatitis; serum sickness; drug hypersensitivity reactions.
Pemphigus; bullous dermatitis herpetiformis; severe erythema multiforme Stevens-Johnson syndrome ; exfoliative erythroderma; mycosis fungoides. To induce diuresis or remission of proteinuria in nephrotic syndrome in adults with lupus erythematosus and in adults and pediatric populations, with idiopathic nephrotic syndrome, without uremia. Primary or secondary adrenocortical insufficiency hydrocortisone or cortisone is the first choice; synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy mineralocorticoid supplementation is of particular importance ; congenital adrenal hyperplasia; hypercalcemia associated with cancer; nonsuppurative thyroiditis.
To tide the patient over a critical period of the disease in: ulcerative colitis; regional enteritis. Idiopathic thrombocytopenic purpura in adults; selected cases of secondary thrombocytopenia; acquired autoimmune hemolytic anemia; pure red cell aplasia; Diamond-Blackfan anemia. For the treatment of acute leukemia and aggressive lymphomas in adults and children.
Uveitis and ocular inflammatory conditions unresponsive to topical corticosteroids; temporal arteritis; sympathetic ophthalmia. Studies support the efficacy of systemic corticosteroids for the treatment of these conditions: allergic bronchopulmonary aspergillosis, idiopathic bronchiolitis obliterans with organizing pneumonia. As adjunctive therapy for short term administration to tide the patient over an acute episode or exacerbation in: psoriatic arthritis; rheumatoid arthritis, including juvenile rheumatoid arthritis selected cases may require low dose maintenance therapy ; ankylosing spondylitis; acute and subacute bursitis; acute nonspecific tenosynovitis; acute gouty arthritis; epicondylitis.
For the treatment of systemic lupus erythematosus, dermatomyositis polymyositis , polymyalgia rheumatica, Sjogren's syndrome, relapsing polychondritis, and certain cases of vasculitis. Tuberculous meningitis with subarachnoid block or impending block, tuberculosis with enlarged mediastinal lymph nodes causing respiratory difficulty, and tuberculosis with pleural or pericardial effusion appropriate antituberculous chemotherapy must be used concurrently when treating any tuberculosis complications ; trichinosis with neurologic or myocardial involvement; acute or chronic solid organ rejection with or without other agents.
In patients on corticosteroid therapy subjected to unusual stress, increased dosage of rapidly acting corticosteroids before, during and after the stressful situation is indicated. Average and large doses of hydrocortisone or cortisone can cause elevation of blood pressure, salt and water retention, and increased excretion of potassium.
These effects are less likely to occur with the synthetic derivatives except when used in large doses. Dietary salt restriction and potassium supplementation may be necessary.
All corticosteroids increase calcium excretion. Corticosteroids can produce reversible hypothalamic-pituitary adrenal HPA axis suppression with the potential for glucocorticosteroid insufficiency after withdrawal of treatment. Metabolic clearance of corticosteroids is decreased in hypothyroid patients and increased in hyperthyroid patients. Changes in thyroid status of the patient may necessitate adjustment in dosage. Persons who are on drugs which suppress the immune system are more susceptible to infections than healthy individuals.
There may be decreased resistance and inability to localize infection when corticosteroids are used. Infection with any pathogen including viral, bacterial, fungal, protozoan or helminthic infection, in any location of the body, may be associated with the use of corticosteroids alone or in combination with other immunosuppressive agents that affect humoral or cellular immunity, or neutrophil function.
These infections may be mild to severe, and, with increasing doses of corticosteroids, the rate of occurrence of infectious complications increases. Corticosteroids may also mask some signs of infection after it has already started. Chicken pox and measles, for example, can have a more serious or even fatal course in non-immune children or adults on corticosteroids.
In such children or adults who have not had these diseases, particular care should be taken to avoid exposure. How the dose, route and duration of corticosteroid administration affect the risk of developing a disseminated infection is not known. If exposed to chicken pox, prophylaxis with varicella zoster immune globulin VZIG may be indicated.
If exposed to measles, prophylaxis with immunoglobulin IG may be indicated. If chicken pox develops, treatment with antiviral agents should be considered. Use of corticosteroids may produce posterior subcapsular cataracts, glaucoma with possible damage to the optic nerves, and may enhance the establishment of secondary ocular infections due to bacteria, fungi or viruses.
The use of oral cortico-steroids is not recommended in the treatment of optic neuritis and may lead to an increase in the risk of new episodes.
Corticosteroids should not be used in active ocular herpes simplex. Latent disease may be activated or there may be an exacerbation of intercurrent infections due to pathogens, including those caused by Candida, Mycobacterium, Ameba, Toxoplasma, Pneumocystis, Cryptococcus, Nocardia, etc.
Corticosteroids may activate latent amebiasis. Therefore, it is recommended that latent or active amebiasis be ruled out before initiating corticosteroid therapy in any patient who has spent time in the tropics or in any patient with unexplained diarrhea.
Similarly, corticosteroids should be used with great care in patients with known or suspected Strongyloides threadworm infestation. In such patients, corticosteroid-induced immunosuppression may lead to Strongyloides hyperinfection and dissemination with widespread larval migration, often accompanied by severe enterocolitis and potentially fatal gram-negative septicemia.
The use of prednisolone in active tuberculosis should be restricted to those cases of fulminating or disseminated tuberculosis in which the corticosteroid is used for the management of the disease in conjunction with an appropriate antituberculous regimen.
If corticosteroids are indicated in patients with latent tuberculosis or tuberculin reactivity, close observation is necessary as reactivation of the disease may occur. During prolonged corticosteroid therapy, these patients should receive chemoprophylaxis. Administration of live or live, attenuated vaccines is contraindicated in patients receiving immunosuppressive doses of corticosteroids. Killed or inactivated vaccines may be administered, however, the response to such vaccines can not be predicted.
Immunization procedures may be undertaken in patients who are receiving corticosteroids as replacement therapy, e. The lowest possible dose of corticosteroid should be used to control the condition under treatment, and when reduction in dosage is possible, the reduction should be gradual. There is an enhanced effect of corticosteroids in patients with hypothyroidism and in those with cirrhosis.
Kaposi's sarcoma has been reported to occur in patients receiving corticosteroid therapy, most often for chronic conditions. Discontinuation of corticosteroids may result in clinical improvement. As sodium retention with resultant edema and potassium loss may occur in patients receiving corticosteroids, these agents should be used with caution in patients with hypertension, congestive heart failure, or renal insufficiency.
Drug-induced secondary adrenocortical insufficiency may be minimized by gradual reduction of dosage. This type of relative insufficiency may persist for months after discontinuation of therapy; therefore, in any situation of stress occurring during that period, hormone therapy should be reinstituted. Steroids should be used with caution in nonspecific ulcerative colitis, if there is a probability of impending perforation, abscess or other pyogenic infection; diverticulitis; fresh intestinal anastomoses; active or latent peptic ulcer.
Signs of peritoneal irritation following gastrointestinal perforation in patients receiving corticosteroids may be minimal or absent. Corticosteroids decrease bone formation and increase bone resorption both through their effect on calcium regulation i. This, together with a decrease in the protein matrix of the bone secondary to an increase in protein catabolism, and reduced sex hormone production, may lead to inhibition of bone growth in children and adolescents and the development of osteoporosis at any age.
Special consideration should be given to patients at increased risk of osteoporosis i. Although controlled clinical trials have shown corticosteroids to be effective in speeding the resolution of acute exacerbations of multiple sclerosis, they do not show that they affect the ultimate outcome or natural history of the disease. The studies do show that relatively high doses of corticosteroids are necessary to demonstrate a significant effect.
An acute myopathy has been observed with the use of high doses of corticosteroids, most often occurring in patients with disorders of neuromuscular transmission e.
This acute myopathy is generalized, may involve ocular and respiratory muscles, and may result in quadriparesis. Elevation of creatinine kinase may occur. Clinical improvement or recovery after stopping corticosteroids may require weeks to years. Psychic derangements may appear when corticosteroids are used, ranging from euphoria, insomnia, mood swings, personality changes, and severe depression, to frank psychotic manifestations.
Also, existing emotional instability or psychotic tendencies may be aggravated by corticosteroids. Intraocular pressure may become elevated in some individuals. If steroid therapy is continued for more than 6 weeks, intraocular pressure should be monitored. Patients should be warned not to discontinue the use of Prednisolone Sodium Phosphate Oral Solution 15 mg Prednisolone per 5 mL abruptly or without medical supervision, to advise any medical attendants that they are taking Prednisolone Sodium Phosphate Oral Solution 15 mg Prednisolone per 5 mL , and to seek medical advice at once should they develop fever or other signs of infection.
Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.
Drugs such as barbiturates, phenytoin, ephedrine, and rifampin, which induce hepatic microsomal drug metabolizing enzyme activity may enhance metabolism of prednisolone and require that the dosage of Prednisolone Sodium Phosphate Oral Solution 15 mg Prednisolone per 5 mL be increased. Increased activity of both cyclosporin and corticosteroids may occur when the two are used concurrently.
Convulsions have been reported with this concurrent use. Estrogens may decrease the hepatic metabolism of certain corticosteroids thereby increasing their effect. Coadministration of corticosteroids and warfarin usually results in inhibition of response to warfarin, although there have been some conflicting reports.
Therefore, coagulation indices should be monitored frequently to maintain the desired anticoagulant effect. Concomitant use of aspirin or other non-steroidal anti-inflammatory agents and corticosteroids increases the risk of gastrointestinal side effects.
❾-50%}Prednisolone syrup storage. prednisolone 15 mg/5 mL oral solution
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This leaflet answers some common questions about PredMix Oral Liquid. It does not contain all the information that is known about PredMix Oral Liquid. All medicines have risks and benefits. Your doctor has weighed the risks of you taking PredMix Oral Liquid against the benefits they expect it will have for you. PredMix Oral Liquid contains prednisolone sodium phosphate which is changed to prednisolone after it enters the body.
Prednisolone belongs to a group of medicines called corticosteroids. It is a synthetic version of a naturally occurring body hormone called cortisol. It works by entering inflammatory cells and blocking the inflammatory reaction. This medicine is only able to prevent or reduce symptoms of your condition, it does not cure it.
PredMix Oral Liquid is used in the treatment of many different conditions. Some of these conditions include: severe allergies, severe or chronic asthma, skin problems, arthritis, inflammatory diseases of the bowel, cancer and "auto-immune" diseases.
PredMix Oral Liquid is also used to prevent or reduce the symptoms of inflammation such as swelling, redness, pain, tenderness or itching in any part of the body.
These symptoms can occur in response to injury or can be caused by many different conditions. Ask your doctor if you have any questions about why PredMix Oral Liquid has been prescribed for you. Your doctor may have prescribed it for another reason. Symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty in breathing; swelling of the face, lips, tongue or any other parts of the body; rash, itching or hives on the skin. Do not take it if you have a current serious or uncontrolled infection, including fungal infections.
Do not take PredMix Oral Liquid after the expiry date printed on the label. It may have no effect at all or an entirely unexpected effect if you take it after the expiry date. Do not take this medicine to treat any other complaints unless your doctor has instructed you to do so. Tell your doctor if you are allergic to any other medicines or any foods, dyes or preservatives. Do not take PredMix Oral Liquid if you are pregnant or plan to become pregnant. It is not generally recommended for use in pregnant women unless the benefits of treatment outweigh the risk to the unborn baby.
Do not take it if you are breast feeding or plan to breast feed. It is not recommended for use while breast feeding as this medicine is found in breast milk. If you have not told your doctor about any of these things, tell them before you take PredMix Oral Liquid. Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from your pharmacy, supermarket or health food shop.
These medicines may be affected by PredMix Oral Liquid or may affect how well it works. You may need to take different amounts of your medicine or you may need to take different medicines. Your doctor or pharmacist has a more complete list of medicines to be careful with or avoid while taking this medicine. If possible, children should not be exposed to common childhood illnesses such as chickenpox or measles while they are taking this medicine. They may suffer from more serious attacks of these illnesses if such exposure occurs.
Children should not be vaccinated with "live" vaccines against common childhood illnesses while they are taking it, as this may result in severe attacks of these illnesses. Potentially serious side effects can occur in children and growing teenagers who are taking corticosteroids. Some of these include obesity, slowed growth, osteoporosis softening of the bone and changes in the adrenal glands. Follow all directions given to you by your doctor and pharmacist carefully. These directions may differ from the information contained in this leaflet.
The dose will depend on the condition being treated and your response to the treatment. Your initial dose will be maintained or adjusted until a satisfactory response is noted. Your dose of PredMix Oral Liquid can be mixed with milk, cordial, soft drink, soft food or you can take it by itself. You will soon know how you prefer to take the medicine. How often PredMix Oral Liquid can be taken may vary depending on what condition is being treated. It can be taken once daily, several times a day or on alternate days.
If you take it once a day or every second day, then it is best taken at breakfast time. If it needs to be taken more than once a day, then space it out during the day. Continue taking PredMix Oral Liquid for as long as your doctor tells you.
This will depend on your condition and on your response to treatment. Some people will need this medicine for only short periods of time whilst others may require long term therapy.
Do not miss any doses and do not stop taking the medicine even if you feel better. Missing doses may make your symptoms worse. Individuals will vary greatly in their response to PredMix Oral Liquid. Your doctor will check your progress at regular intervals. If you miss a dose of this medicine the decision of whether you should take it or not will depend on how many times a day you take PredMix Oral Liquid.
Immediately telephone your doctor or Poisons Information Centre telephone 13 11 26 for advice, or go to Accident and Emergency at the nearest hospital if you think that you or anyone else may have taken too much PredMix Oral Liquid. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Take PredMix Oral Liquid exactly as your doctor has prescribed. If you do not follow your doctor's instructions you may not get improvement in the symptoms of your condition.
Try not to miss any doses and take the medicine even if you feel well. Tell your doctor if your condition returns or becomes worse after your dose of PredMix Oral Liquid has been reduced or treatment has been stopped. Tell any other doctors, dentists and pharmacists who are treating you that you are taking PredMix Oral Liquid, especially if you are being started on any new medicines. Tell your doctor, surgeon or dentist that you are taking PredMix Oral Liquid if you are about to undergo surgery or an operation.
Your dose of this medicine may need to be increased to cover you during the stress of an operation. Tell your doctor straight away if you are a diabetic, and you notice a change in the results of your blood or urine sugar tests. This medicine may affect your blood sugar levels as it can affect the body's ability to handle glucose.
For diabetics, this means that your diabetes may become more severe. For others, diabetes may develop for the first time while taking corticosteroids such as PredMix Oral Liquid. If you have been taking it for a long time your doctor may gradually reduce the amount you are taking over a period of several days, weeks or months before stopping completely.
Do not stop taking PredMix Oral Liquid suddenly unless advised by your doctor. If you stop taking it suddenly, the symptoms of your condition may return or you may develop symptoms of cortisol deficiency such as fainting, weakness, restlessness, nausea, vomiting, headache, dizziness, muscle weakness or joint pain.
Do not have any immunisations particularly with "live" vaccines such as measles, oral polio or yellow fever without your doctor's approval while you are being treated with PredMix Oral Liquid.
Avoid close contact with anyone who has a contagious disease such as measles or chickenpox. Exposure to such diseases while you are taking this medicine, particularly if large doses are being taken, can put you at greater risk of developing these diseases if you have not had them before.
Tell your doctor straight away if you think you have been exposed to chickenpox or measles. As with any new medicine, you should take care when driving, operating machinery or drinking alcohol until you know how PredMix Oral Liquid affects you.
Check with your doctor or pharmacist before drinking alcohol while you are taking this medicine. If you drink alcohol while taking it you may find that stomach problems occur.
The signs and symptoms of infections such as fever or inflammation may be hidden by the anti-inflammatory action of PredMix Oral Liquid. You should see your doctor for medical advice for any but the most minor infections. Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking PredMix Oral Liquid.
PredMix Oral Liquid helps most people who take it but it may have unwanted side effects in some people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
When PredMix Oral Liquid is taken for short periods of time it is unlikely to cause any problems. When PredMix Oral Liquid is taken for long periods of time and in high doses the risk of side effects is greater. Tell your doctor immediately or go to casualty at your nearest hospital if you notice any of the following symptoms:. These are all serious side effects of PredMix Oral Liquid which may occur with high doses and long term use. You may need urgent medical attention or hospitalisation.
Some side effects can only be detected by your doctor. So it is important to visit your doctor for regular check-ups when PredMix Oral Liquid is taken for long periods of time. Tell your doctor if you notice anything else that is making you feel unwell.
Some people may get other side effects while using PredMix Oral Liquid. If your doctor tells you to stop taking PredMix Oral Liquid, or you find that the expiry date has passed, ask your pharmacist what to do with any liquid you have left over.
PredMix Oral Liquid contains 7. Predmix contains the active ingredient prednisolone sodium phosphate 7. It contains excipients with known effect, methyl hydroxybenzoate and propyl hydroxybenzoate. For the full list of excipients, see Section 6. Predmix is a clear, colourless liquid, free from haze and substantially free from particulate matter.
Store in a refrigerator (2°C - 8°C). Once opened, store below 25°C and use within 3 months. Keep the container in the outer carton in order to. USUAL DOSAGE: See accompanying circular. Dispense in tight, light-resistant and child-resistant containers as defined in USP. Store at 20° to 25°C (68° to 77°F). Store at 2° to 25°C (36° to 77°F). May be refrigerated. Keep tightly closed and out of the reach of children. Dispense in tight, light-resistant glass or PET. Most solutions or syrups are stored. Store this medication according to the directions on the product package away from light and moisture. Some brands must be refrigerated, and others must be. Idiopathic thrombocytopenic purpura in adults; selected cases of secondary thrombocytopenia; acquired autoimmune hemolytic anemia; pure red cell aplasia; Diamond-Blackfan anemia. You may need urgent medical attention or hospitalisation. Aspirin should be used cautiously in conjunction with corticosteroids in patients suffering from hypothrombinemia. Forgot password?The photos shown are samples only Not all photos of the drug may be displayed. Your medication may look different. If you have questions, ask your pharmacist.
Generic name: Prednisolone liquid - oral. Pronunciation pred-NIS-oh-loan. Brand name s Orapred , Pediapred , Prelone. Prednisolone is a man-made form of a natural substance corticosteroid hormone made by the adrenal gland. It is used to treat conditions such as arthritis, blood problems, immune system disorders, skin and eye conditions, breathing problems, cancer, and severe allergies. It decreases your immune system's response to various diseases to reduce symptoms such as pain, swelling and allergic-type reactions.
Take this medication by mouth, with food or milk to prevent stomach upset, exactly as directed by your doctor. Do not use a household spoon because you may not get the correct dose. There are many brands, strengths, and forms of liquid prednisolone available.
Read the dosing instructions carefully for each product because the amount of prednisolone may be different between products. See also Precautions and Storage sections. Follow the dosing schedule carefully. The dosage and length of treatment are based on your medical condition and response to treatment. Your doctor may direct you to take prednisolone 1 to 4 times a day or take a single dose every other day.
It may help to mark your calendar with reminders. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased. If you suddenly stop using this medication, you may have withdrawal symptoms such as weakness, weight loss, nausea, muscle pain, headache, tiredness, dizziness.
To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used prednisolone for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal. See also Precautions section.
Nausea, heartburn, headache, dizziness, menstrual period changes, trouble sleeping, increased sweating, or acne may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Because this drug works by weakening the immune system, it may lower your ability to fight infections. This may make you more likely to get a serious rarely fatal infection or make any infection you have worse.
Tell your doctor right away if you have any signs of infection such as cough, sore throat, fever, chills. Use of this medication for prolonged or repeated periods may result in oral thrush or a yeast infection. Contact your doctor if you notice white patches in your mouth or a change in vaginal discharge.
This medication may rarely make your blood sugar rise, which can cause or worsen diabetes. If you already have diabetes, check your blood sugar regularly as directed and share the results with your doctor. Your doctor may need to adjust your diabetes medication, exercise program, or diet. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:. This is not a complete list of possible side effects.
If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects.
You may report side effects to Health Canada at Before taking prednisolone, tell your doctor or pharmacist if you are allergic to it; or to prednisone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of:. This drug may make you dizzy. Alcohol or marijuana cannabis can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana cannabis. This medicine may cause stomach bleeding.
Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. Consult your doctor or pharmacist for more information. Before having surgery, tell your doctor or dentist about all the products you use including prescription drugs, nonprescription drugs, and herbal products.
Ask your doctor or pharmacist about using this product safely. Using corticosteroid medications for a long time can make it more difficult for your body to respond to physical stress.
If you will be using this medication for a long time, carry a warning card or medical ID bracelet that identifies your use of this medication. This medication may mask signs of infection. It can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others such as chickenpox, measles, flu.
Consult your doctor if you have been exposed to an infection or for more details. Avoid contact with people who have recently received live vaccines such as flu vaccine inhaled through the nose. This medication may slow down a child's growth if used for a long time.
Consult the doctor or pharmacist for more details. See the doctor regularly so your child's height and growth can be checked. During pregnancy, prednisolone should be used only when clearly needed. It may rarely harm an unborn baby. Discuss the risks and benefits with your doctor. Infants born to mothers who have been using this medication for an extended period of time may have hormone problems. This medication passes into breast milk. However, this drug is unlikely to harm a nursing infant.
Consult your doctor before breast-feeding. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Other medications can affect the removal of prednisolone from your body, which may affect how prednisolone works. Examples include estrogens, azole antifungals such as itraconazole , rifamycins such as rifabutin , St.
John's wort, drugs used to treat seizures such as phenytoin , among others. If your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention usually milligrams a day , you should continue taking it unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details. This product may interfere with certain lab tests such as skin tests. Make sure laboratory personnel and all your doctors know you use this drug.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call Otherwise, call a poison control center right away. US residents can call their local poison control center at Canada residents can call a provincial poison control center.
Consult your doctor for more details. This medication may cause bone problems osteoporosis. Lifestyle changes that may help reduce the risk of bone problems while taking this drug for an extended time include doing weight-bearing exercise, getting enough calcium and vitamin D, stopping smoking, and limiting alcohol.
Discuss with your doctor lifestyle changes that might benefit you. If you are taking this medication once daily and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. If you are taking this medication every other day, ask your doctor or pharmacist what you should do if you miss a dose. Store this medication according to the directions on the product package away from light and moisture.
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