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Betamethasone Sodium Phosphate and Betamethasone Acetate / Products / American Regent
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Drug information provided by: IBM Micromedex. It is very important that your doctor check you or your child's progress at regular visits to make sure this medicine is working properly and to decide if you should continue to receive it. Blood or urine tests may be needed to check for unwanted effects. This medicine may cause a serious allergic reaction, called anaphylaxis.
This can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after receiving this medicine. Your blood pressure might get too high while you are using this medicine. This may cause headaches, dizziness, or blurred vision.
You might need to measure your blood pressure at home. If you think your blood pressure is too high, call your doctor right away. Receiving too much of this medicine or receiving it for a long time may increase your and your child's risk of having adrenal gland problems.
Talk to your doctor right away if you or your child have more than one of these symptoms while receiving this medicine: blurred vision, dizziness or fainting, a fast, irregular, or pounding heartbeat, increased thirst or urination, irritability, or unusual tiredness or weakness. This medicine may cause you or your child to get more infections than usual.
Avoid people who are sick or have infections and wash your hands often. If you or your child are exposed to chickenpox or measles, tell your doctor right away. If you or your child start to have a fever, chills, sore throat, or any other sign of an infection, call your doctor right away.
Tell your doctor if you or your child have recently spent time in a tropical climate or have unexplained diarrhea before receiving this medicine. While you are being treated with betamethasone sodium phosphate and betamethasone acetate combination injection, do not have any immunizations vaccines without your doctor's approval. Betamethasone may lower your body's resistance and the vaccine may not work as well or you might get the infection the vaccine is meant to prevent.
In addition, you should not be around other persons living in your household who receive live virus vaccines because there is a chance they could pass the virus on to you.
Some examples of live vaccines include measles, mumps, influenza nasal flu vaccinepoliovirus oral formrotavirus, and rubella. Do not get close to them and do not stay in the same room with them for very long. If you have questions about this, talk to your doctor. Check with your doctor right away if blurred vision, difficulty in reading, eye pain, or any other change in vision occurs during treatment with this medicine for more than 6 weeks.
Your doctor may want you to have your eyes checked by an ophthalmologist eye doctor. This medicine may increase your risk for cancer eg, Kaposi's sarcoma when used for a long time. Talk with your doctor if you have concerns. This medicine may increase your risk for stomach or bowel perforation tear or hole. Check with your doctor right away if you have stomach cramps or pain, black, tarry stools, diarrhea, fever, or severe vomiting, sometimes with blood.
If you receive this medicine for a long time, tell your doctor about any extra stress or anxiety in your life, including other health concerns and emotional stress.
Your dose of this medicine might need to be changed for a short time while you have extra stress. This medicine might cause thinning of the bones osteoporosis or slow growth in children if used for a long time. Tell your doctor if you have any bone pain or if you have an increased risk for osteoporosis.
If your child is using this medicine, tell the doctor if you think your child is not growing properly. This medicine may cause changes in mood or behavior for some patients. Tell your doctor right away if you or your child have depression, mood swings, a false or unusual sense of well-being, trouble with sleeping, or personality changes while receiving this medicine. Make sure any doctor or dentist who treats you knows that you are receiving this medicine.
This medicine may affect the results of certain skin tests. Do not stop receiving this medicine suddenly without checking first with your doctor. Your doctor may want you or your child to gradually reduce the amount you are receiving before stopping it completely.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription over-the-counter [OTC] medicines and herbal or vitamin supplements. There is a problem with information submitted for this request. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID, plus expertise on managing health. To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you.
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This site complies with the HONcode standard for trustworthy health information: verify here. This content does not have an English version. This content does not have an Arabic version. See more conditions. Products and services. Precautions Drug information provided by: IBM Micromedex It is very important that your doctor check you or your child's progress at regular visits to make sure this medicine is working properly and to decide if you should continue to receive it.
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Many cases were temporally associated with the corticosteroid injection; reactions occurred within minutes to 48 hours after injection. Chronic corticosteroid therapy e. Endocrine: Decreased carbohydrate and glucose tolerance, development of cushingoid state, glucosuria, hirsutism, hypertrichosis, increased requirements for insulin or oral hypoglycemic adrenocortical and pituitary unresponsiveness, suppression of growth in pediatric patients. Mannitol itself can cause hypernatremia. Healthcare providers are advised to discontinue corticosteroid therapy and observe a sufficient washout period before administering macimorelin. Killed or inactivated vaccines may be administered.
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Synthetic glucocorticoid with little mineralocorticoid activity Used as an antiinflammatory or immunosuppressive agent; available systemically injectable and oral Topical formulations are of medium e. Dose range is one-third to one-half the normal corticosteroid oral dose given every 12 hours. Dose range is one-third to one-half the normal oral dose given every 12 hours. Up to 9 mg IV or IM per day may be required, adjust according to patient response.
Corticosteroids are not indicated as initial treatment for anaphylaxis, but can be given as adjunctive therapy after the administration of epinephrine. Dose range is one-third to one-half the normal oral dose, given every 12 hours. Guidelines recommend as adjunct therapy for meningitis. Routine use outside of CNS involvement is not recommended; however, select patients may benefit. Initially, 0. Adjust according to patient response.
Because of the potential complications of steroid use, steroids should be used selectively and in the lowest dose possible for the shortest duration as possible.
For acute gouty arthritis use 0. Dosage depends on the degree of inflammation and the size and location of the affected area.
For bursitis, under calcaneal spur or for bursitis over hallux rigidus or digiti quinti varus give 0. For tenosynovitis, periostitis of cuboid give 0. Up to 9 mg may be used. Repeat as needed. In some cases, twice daily dosage may be necessary. For the 0. Apply twice daily, in the morning and at night. Apply a thin film of a 0. Application 1 to 2 times per day is often effective. Occlusive dressings may be used for the management of recalcitrant conditions, as long as infection is not present.
For 0. Dosage may be increased in stubborn cases. Following improvement, apply lotion once daily. Apply a small amount twice daily to the affected area s of the scalp. Discontinue use when control is achieved. If no improvement within 2 weeks, reassess the diagnosis. Apply topically to the affected area s twice daily. Rub in gently. Do not use on the face, groin, axilla or other intertriginous areas. Do not use if atropy is present at the affected area.
Discontinue treatment once condition is under control. Treatment for longer than 4 weeks is not recommended. Occlusive dressings may be used for the management of psoriasis, as long as infection is not present.
Apply topically to the affected area s of the scalp twice daily, morning and night. Discontinue when control achieved. If no improvement after 2 weeks, re-evaluate diagnosis. Apply twice daily to the affected area s of the scalp, morning and night.
Dosage requirements are variable and must be individualized. After a favorable response is noted, the proper maintenance dosage should be determined by decreasing the initial drug dosage in small decrements at appropriate time intervals until the lowest dosage which will maintain an adequate clinical response is reached. A single course of corticosteroids may also be considered starting at 23 weeks gestation for pregnant women who are at risk of preterm delivery within 7 days, regardless of membrane status.
However, no additional benefit has been demonstrated for courses of antenatal steroids with shorter dosage intervals than those recommended, often referred to as accelerated dosing, even when delivery is imminent.
A repeat or rescue course of corticosteroids may be considered in women who are less than 34 weeks gestation, who are at risk of preterm delivery within the next 7 days, and whose prior course of antenatal corticosteroids was administered more than 14 days previously. Rescue course corticosteroids could be provided as early as 7 days from the prior dose if indicated by clinical situation. Corticosteroid dosage must be individualized and is highly variable depending on the nature and severity of the disease, route of treatment, and on patient response.
Betamethasone dipropionate augmented topical products e. Specific guidelines for dosage adjustments in hepatic impairment are not available; it appears that no dosage adjustments are needed. Specific guidelines for dosage adjustments in renal impairment are not available; it appears that no dosage adjustments are needed. Administer with meals to minimize indigestion or gastric irritation. If given once daily, administer in the morning to coincide with the body's normal cortisol secretion.
Visually inspect parenteral products for particulate matter and discoloration prior to administration whenever solution and container permit. If coadministration of a local anesthetic is desired with betamethasone sodium phosphate; betamethasone acetate injectable suspension, do not use anesthetics containing preservatives e. Similar local anesthetics may also be used. Do not inject the anesthetic into the vial containing betamethasone; withdraw betamethasone into a syringe, then draw the local anesthetic into the same syringe and shake briefly.
Direct intravenous injection: Use only betamethasone sodium phosphate. Administer slowly into a vein over at least 1 minute. Intermittent intravenous infusion: Use only betamethasone sodium phosphate.
Infuse slowly at a rate prescribed by the physician. Betamethasone sodium phosphate; betamethasone acetate injectable suspension may be administered intramuscularly. Intra-articular, Intra-bursal, Intradermal, or Intralesional injection Administration of betamethasone via these routes require specialized techniques.
Only clinicians familiar with these methods of administration and with management of potential complications should administer betamethasone by these routes. For acute subdeltoid, subacromial, olecranon, and prepatellar bursitis, inject into the affected tendon sheaths rather than into the tendons themselves.
In ganglions of joint capsules and tendon sheaths, injection of 0. For intra-articular injection, insert a to gauge needle on an empty syringe into the synovial cavity and withdraw a few drops of synovial fluid to confirm that the needle is in the joint.
Replace the aspirating syringe with a syringe containing betamethasone suspension, and inject into the joint. For intralesional treatment, inject betamethasone suspension intradermally not subcutaneously using a tuberculin syringe with a gauge, half-inch needle. Care should be taken to deposit a uniform depot of medication intradermally. A tuberculin syringe with a gauge, three-fourth-inch needle is suitable for most injections into the foot. Betamethasone dipropionate and valerate are used topically.
Betamethasone valerate may be used with occlusive dressings for the management of psoriasis or recalcitrant conditions. Betamethasone dipropionate in augmented vehicles should NOT be used with occlusive dressings; instruct patients using these formulations not to bandage, cover, or wrap area in any way that may be occlusive.
Using gloves, apply sparingly in a thin film and rub gently into the cleansed, slightly moist affected area. Gel: Using gloves, apply sparingly in a thin film and rub gently into the cleansed, slightly moist affected area.
Scalp foam: Invert can and dispense a small amount of foam onto a saucer or other cool surface. Do not dispense directly onto hands because foam will begin to melt immediately upon contact with warm skin. Pick up small amounts of foam with fingers and gently massage into affected area until foam disappears. Repeat until entire affected scalp area is treated. Topical Spray: Avoid use on the face, scalp, axilla, groin, or other intertriginous areas. Shake well before use.
Wash hands before and after treatment. Spray directly onto the affected skin areas; rub in gently but completely. Once spray is in use, any unused spray should be discarded after 28 days. Acute adrenal insufficiency and even death may occur following abrupt discontinuation of prolonged systemic therapy.
In addition, a withdrawal syndrome unrelated to adrenocortical insufficiency may occur following sudden discontinuation of corticosteroid therapy. These effects are thought to be due to the sudden change in glucocorticoid concentration rather than to low corticosteroid levels. Withdrawal from prolonged systemic corticosteroid therapy should be gradual.
HPA suppression can last for up to 12 months following cessation of systemic therapy. Recovery of HPA axis function is generally prompt and complete upon discontinuation of the topical corticosteroid. HPA-suppressed patients may need supplemental corticosteroid treatment during periods of physiologic stress, such as surgical procedures, acute blood loss, or sepsis, even after the corticosteroid has been discontinued.
The naturally occurring corticosteroids i. Conditions that increase systemic absorption of topical corticosteroids include use over large surface areas, prolonged use, use in areas where the epidermal barrier is disrupted i. Occlusive dressings should not be used with augmented formulations of topical betamethasone e. Diapers or plastic pants may be considered occlusive dressings, therefore, topical betamethasone should not be used for the treatment of diaper dermatitis. If these effects are noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent corticosteroid.
The efficacy and safety of corticosteroids in the pediatric population are based on the well-established course of effect of corticosteroids, which is similar in children and adult populations.
localhost › drugs-supplements › description › drg This medicine may increase your risk for stomach or bowel perforation (tear or hole). Check with your doctor right away if you have stomach.
An equal mixture of two betamethasone salts, Celestone Soluspan, allows for both immediate and delayed corticosteroid responses. Betamethasone sodium phosphate. Betamethasone sodium phosphate and betamethasone acetate combination is a corticosteroid (cortisone-like medicine or steroid). It works on the. Betamethasone sodium phosphate, a soluble ester, provides prompt activity, while betamethasone acetate is only slightly soluble and affords.
Iopamidol: Contraindicated Because both intrathecal corticosteroids i. Coadministration may significantly increase betamethasone exposure increasing the risk for Cushing's syndrome and adrenal suppression. Tell any doctor or dentist who treats you that you are using this medicine. Dextromethorphan; Bupropion: Moderate Monitor for seizure activity during concomitant bupropion and corticosteroid use. The efficacy and safety of corticosteroids in the pediatric population are based on the well-established course of effect of corticosteroids, which is similar in children and adult populations.
Drug information provided by: IBM Micromedex. Betamethasone sodium phosphate and betamethasone acetate combination injection provides relief for inflamed areas of the body. It is used to treat a number of different conditions, such as inflammation swelling , severe allergies, adrenal problems, arthritis, lung or breathing problems, blood or bone marrow problems, eye or vision problems, lupus, serious skin conditions, kidney problems, ulcerative colitis, and flare-ups of multiple sclerosis.
Betamethasone sodium phosphate and betamethasone acetate combination is a corticosteroid cortisone-like medicine or steroid. It works on the immune system to help relieve swelling, redness, itching, and allergic reactions. There is a problem with information submitted for this request.
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All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission.
Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. This site complies with the HONcode standard for trustworthy health information: verify here. This content does not have an English version. This content does not have an Arabic version. See more conditions. Products and services.
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